Adults concerned they may have celiac disease, first-degree relatives of people with celiac disease and individuals with an associated autoimmune disorder or other condition, especially Type 1 diabetes mellitus, autoimmune thyroid disease, autoimmune liver disease, Down syndrome, Turner syndrome, Williams syndrome and selective immunoglobulin A (IgA) deficiency should be tested for celiac disease.⁴

Celiac disease can be serious and being undiagnosed and untreated with a gluten-free diet can cause long-term complications such as anemia, malnutrition, poor bone health and increased risk of other autoimmune disorders.⁷

This Celiac Disease Antibody Test is the first step in screening for celiac disease. Our test screens for celiac disease by measuring your antibody levels. If your results suggest celiac disease is possible or likely, talk to your healthcare provider who may consider further testing in order to diagnosis celiac disease with a small bowel biopsy.

Symptoms for both celiac disease and non-celiac gluten sensitivity can be similar to one another and may be improved by a gluten-free diet. However, only people with celiac disease will test positive for antibodies specific to the autoimmune disorder involving inflammation and damage to the small intestine.⁸

This test measures your total immunoglobulin A (IgA) and IgA antibodies to tTG (tissue transglutaminase). If your total IgA levels are low or deficient, a second test is conducted to examine levels of IgG antibodies to tTG (tissue transglutaminase) and IgG antibodies to DGP (deamidated gliadin peptide).

When taking this test, it is important to currently have gluten in your diet in order for accurate testing and results. If you have celiac disease and are on a gluten-free diet for two or more weeks, your celiac antibodies will decrease over time and may be undetectable.

If your results suggest celiac disease is possible or likely, you should share your results and any symptoms you are having with your healthcare provider. Your healthcare provider can determine if additional testing is necessary and discuss next steps on how to improve your health and wellness.

If your initial results indicate celiac disease is unlikely but you have a first-degree relative with celiac disease, it is reasonable to repeat this celiac antibody test in 4-5 years because celiac disease can develop at any age in people who are genetically susceptible.⁹

Your testing will be performed in a CLIA-certified clinical laboratory. Labcorp provides leading-edge medical laboratory tests and services through a national network of primary clinical laboratories and specialty testing laboratories. Our labs perform regular quality assurance testing to ensure our results are accurate.

Your results will be provided to you through our secure online portal to view or print. Results are also made available through a secure portal to the independent healthcare provider who placed your test order.  If you are accessing your results through your Labcorp Patient™ account, all users linked to the account will have access to all OnDemand test results. Results may also be provided to a local, state, and/or federal health authority; for example, many states require the testing laboratory and physician to report test results for certain communicable diseases, such as COVID-19, to local or state health departments.

If you have questions or comments regarding the Labcorp Notice of Privacy Practices, or have a complaint about our use or disclosure of your PHI or our privacy practices, please contact: privacyofficer@labcorp.com, call us at (877) 234-4722 (877-23-HIPAA) and ask for the Labcorp HIPAA Privacy Officer, or send a written request to: HIPAA Privacy Officer, Labcorp, 531 South Spring Street, Burlington, NC 27215. You also may file a complaint with the Secretary of the U.S. Department of Health and Human Services.

Visit the Labcorp OnDemand® website to browse and purchase laboratory tests and create your Labcorp Patient™ account to view your results. All Labcorp OnDemand testing requires an order from an authorized healthcare professional. For your convenience, Labcorp OnDemand has contracted with independent professional entities (collectively, Providers) to deliver healthcare provider services. Visit a Labcorp location for sample collection; or, if using an at-home collection kit, collect your sample yourself. We’ll let you know when your results are ready and can be accessed through your Labcorp Patient™ account.