All Tests, General Health, Annual Wellness
Man discusses prostate cancer screening with healthcare provider.

PSA Prostate Cancer Screening Test

$ 69.0

Are you concerned about prostate cancer? Consider getting a PSA screening.

All men are at risk for prostate cancer—you have the option be proactive.  

More than 10% of men in the U.S. develop prostate cancer in their lifetime.¹ Our PSA (prostate-specific antigen) Prostate Cancer Screening Test measures the level of prostate-specific antigen in your blood. Knowing your PSA number can help you and your healthcare provider figure out if further testing or treatment should be considered because an elevated PSA may be a sign of prostate cancer.  
Age is the most common risk factor—the older you are, the greater the chance is of having prostate cancer. Many men with prostate cancer don’t show early symptoms and may not even know they have the disease.²
Note: This test does not indicate whether or not you have prostate cancer—but it gives proactive insight into your overall prostate health, which could lead to earlier diagnosis and better outcomes in some men with the disease.¹ This test is not intended for those who have undergone prostatectomy or those who have known prostate conditions. Talk to your healthcare provider to discuss if the PSA screening test is right for you. See below and in the FAQs for guideline recommendations and the benefits/risks of PSA screening. 

Test Details

Sample Type: Blood
Age: 18+
HSA/FSA: Accepted
Collection Method: In person at a Labcorp location
Results: 1-2 days from when your sample arrives at our lab

Preparation: No special preparation needed.

What's Tested
Prostate Specific Antigen (PSA)

A protein produced by both healthy and cancerous cells in the prostate gland.

Patient Service Centers

Labs in more than 2,000 locations across the country.

Circular blue dot design background.


The prostate is a small gland that plays a major role in your reproductive function. It produces prostatic fluid, which prolongs the lifespan of sperm and contributes to the volume of semen.

Major medical associations and societies, including the US Preventive Services Task Force, American Cancer Society, American Urological Association, agree that men should discuss screening with their health care providers. They also agree that men should be informed about the benefits and risks of prostate cancer screening and treatment and make decisions that best reflect personal values and preferences.⁹


According to the American Cancer Society (ACS), the discussion about screening should take place at:


  • Age 50 for men who are at average risk of prostate cancer and are expected to live at least 10 more years.

  • Age 45 for men at high risk of developing prostate cancer. This includes African Americans and men who have a first-degree relative (father or brother) diagnosed with prostate cancer at an early age (younger than age 65).

  • Age 40 for men at even higher risk (those with more than one first-degree relative who had prostate cancer at an early age).⁵

Screening can provide earlier detection of prostate cancer which could provide the opportunity for more treatment options and better survival odds in some men, but there are also potential risks associated with screening, diagnosis and treatment that should be considered. Possible risks may include false positive results, overdiagnosis of prostate cancer and potential complications from prostate cancer treatment. Detection and treatment of a slow-growing prostate cancer that may have never caused symptoms in the patient’s lifetime can result in complications from the treatment, but no benefit, referred to as overdiagnosis.¹

Yes to both. A false negative result is possible (normal PSA level when in fact the person has prostate cancer). Patients taking certain medications, including finasteride (a.k.a. Propecia) and dutasteride (a.k.a. Avodart) may have a falsely lower PSA level.


A false positive result is possible (elevated PSA level when in fact the person does not have prostate cancer). False positive results may cause patients to worry unnecessarily and may lead to unnecessary additional testing and treatment, so it’s important to be aware of this possibility. Older men are more likely to have false positive results because PSA levels increase with age in otherwise healthy men.⁸ Common benign conditions such as benign prostatic hyperplasia (BPH) can also result in a false positive result. 


As with any kind of screening or testing, you should share and discuss your test results with your healthcare provider.

High levels of PSA may be a sign of prostate cancer. Although this test does contribute to early diagnosis of men with prostate cancer, an elevated PSA test alone does not always indicate cancer. Benign conditions, such as benign prostatic hyperplasia (BPH) and prostatitis, often elevate PSA levels. Furthermore, BPH is much more common than prostate cancer, affecting nearly 70% of men in their 60’s.¹ Older men are more likely to have false positive results (i.e., high PSAs in the absence of cancer) because PSA levels increase with age in otherwise healthy men.²  In some studies, men over 50 with mildly elevated PSAs (4.0 – 10.0 ng/mL) only had a 25% probability of having prostate cancer on biopsy.³


As with any kind of screening or testing, you should share and discuss your test results with your healthcare provider who can help you interpret an abnormal result and determine if further evaluation is indicated.