All Tests, General Health
Woman suffers from chronic fatigue.

Fatigue Test

$ 159.0

Tired of feeling tired? Investigate your chronic fatigue symptoms.

Long term fatigue or feelings of excessive tiredness can cause a decrease in quality of life and overall well-being. Lifestyle factors related to sleep habits, nutrition, exercise, and stress levels can significantly impact your general sense of well-being—but sometimes there is more to the story. If your fatigue has persisted for six months or more, and it does not improve with rest and gets worse with physical or mental activity, it’s time to seek out answers. Your chronic fatigue symptoms may be due to measurable deficiencies or imbalances in your body. 

Labcorp OnDemand’s Fatigue Test can shed light on potential imbalances, providing insights you need to begin investigating your symptoms. 

Note: There is no blood test to diagnose chronic fatigue syndrome. However, this test may provide proactive insight into chemical or functional imbalances that can contribute to extreme fatigue.

Fatigue Test

$ 159.0

Test Details

Sample Type: Blood
Age: 18+
HSA/FSA: Accepted
Collection Method: In person at a Labcorp location
Results: 1 day from when your sample arrives at our lab

Preparation: Fast for 12 hours (no food or drink, except water) before sample collection. If you’re taking a supplement containing biotin (also called vitamin B7 or B8, vitamin H, or coenzyme R), commonly found in products promoting nail, skin, and hair health, it is recommended that you wait at least 72 hours from your last dose before sample collection.

What’s Included in this Package

Thyroid Stimulating Hormone (TSH) Test

Your thyroid is essential to your overall health and wellbeing. Thyroid hormones influence everything from your heart rate to how quickly your body burns calories. They can also influence factors as subtle as your mood or as vital as your fertility.

This TSH blood test measures thyroid stimulating hormone (TSH), which stimulates the thyroid to produce two additional hormones, T4 (thyroxine) and T3 (triiodothyronine), both of which play a critical role in controlling the body’s metabolism. Typically, low or high TSH levels indicate potential problems related to the function of your thyroid. 

Testing your hormones starts with a simple TSH blood test.
Thyroid Stimulating Hormone (TSH)

A hormone that stimulates the thyroid gland to produce T4 (thyroxine) and T3 (triiodothyronine), two hormones that play critical roles in controlling the body’s metabolism. 

Complete Blood Count (CBC) Test

Your blood is perhaps the most essential substance in your body—transporting life-sustaining nutrients, hormones and oxygen all while carrying waste products for removal through the lungs, liver and kidneys. Blood is also your body's most crucial defense against fighting infections.


This complete blood count (CBC) test counts the cells that circulate in your blood, which can provide valuable information to you and your healthcare provider about your overall health. This full blood panel may also be a first step to detecting health conditions such as anemia, inflammation, blood disorders and infection. This panel measures your red blood cells (RBCs), white blood cells (WBCs), and platelets. This is a CBC with differential blood test, which also measures the amount of each type of WBCs that you have in your body (neutrophils, lymphocytes, monocytes, basophils, and eosinophils).


Note: A CBC test is not a diagnostic test and cannot confirm any specific illness or disease. Further testing and medical consultation may be required to determine the cause of abnormal results.

This CBC blood test is the first step to detecting illnesses that can affect your overall health.
Red Blood Count

Measures the number of red blood cells (erythrocytes). Red blood cells contain hemoglobin, a protein that carries oxygen throughout the body.

White Blood Count

Detects the number of white blood cells (leukocytes) in the body, cells that fight off infections and foreign agents that may infect the body.


Measures the amount of hemoglobin in the blood, the oxygen-carrying protein in red blood cells.


Measures the proportion of red blood cells to the fluid component (or plasma) in your blood.

Platelet Count

Measures the number of platelets in the blood, the cell components essential for blood clotting.

Immature Granulocytes

Measures the percent of white blood cells in an early stage of development which are not usually present in significant amounts in the blood.  


Measures the level of monocytes, the type of white blood cells responsible for breaking down germs or bacteria that enter the body.  


Measures the level of lymphocytes, the white blood cells that are vital to producing antibodies and helping the body fight against bacteria, viruses, and other threats.


Measures the level of neutrophils, the type of white blood cells that destroy bacteria and fungi and protect the body from infections.  

Immature Cells

White blood cells in an early stage of development which are not usually present in significant amounts in the blood.  


Measures the quantity of eosinophils in the body, a type of disease-fighting white blood cell. 


Measures the quantity of basophils in your body, a type of white blood cell produced by bone marrow that helps the body fight parasitic infections, prevents blood clotting, and mediates allergic reactions. 

Mean Corpuscular Volume

Measures the average size of the red blood cells themselves. 

Mean Corpuscular Hemoglobin

Measures MCH levels, the average amount of hemoglobin found in the red blood cells in the body. 

Mean Corpuscular Hemoglobin Concentration

Measures MCHC levels, the average weight of hemoglobin based on the volume of red blood cells.

Red Cell Distribution Width

Measures the variation of size and volume of the body’s red blood cells.  

Immature Granulocytes (Absolute)

White blood cells in an early stage of development which are not usually present in significant amounts in the blood.


Diabetes Risk (HbA1c) Test

Standard glucose tests only measure blood sugar levels at the time the sample is collected. This HbA1c (hemoglobin A1c) test measures your average blood sugar level over an extended period (8-12 weeks) and is a useful tool for screening for prediabetes and diabetes.


Knowing your average blood sugar levels serves as a critical indicator of your health. Consistently elevated blood sugar levels often indicate prediabetes and diabetes: a serious disease that can ultimately affect the health and function of other parts of the body including your nervous system, cardiovascular system, eyes and kidneys.

This test helps determine if diabetes may be a concern for you.
Hemoglobin A1c

Measures the average amount of glucose in your blood over an extended period (typically 8-12 weeks).

Comprehensive Metabolic Panel (CMP)

Your metabolism is the life force of all your body’s energy, turning what you eat into the fuel to support vital functions including heart rate, brain function and breathing. A metabolic test can reveal how the pieces involved are working to support your body’s needs. 


This comprehensive metabolic panel (CMP) blood test measures essential components in your blood (including sugars, minerals, electrolytes, enzymes and waste products) that contribute to your overall health and provide information on the functioning status of your metabolism, liver and kidneys. When reviewed by your healthcare provider, a CMP test with a clinical examination may help detect certain health conditions like diabetes, kidney disease, liver inflammation or electrolyte imbalances.  


Note: A CMP panel may reveal results that suggest abnormal thyroid function, but it does not directly measure thyroid function. To assess your thyroid function, consider our Thyroid Stimulating Hormone (TSH) Test or the Thyroid Health Blood Test Package, which also provides TSH results.


The CMP blood test measures key components for insights on your metabolism, liver and kidneys.

An electrically charged mineral (electrolyte) that helps regulate fluid and acid-base balance within the body.

Globulin, Total

A measure of a group of proteins that function to help transport nutrients and help the body fight infections.


A mineral essential to bone and muscle health.

Alkaline Phosphatase

An enzyme found in the cells of the liver and other tissue.

A/G Ratio

A measure of the amount of albumin present compared to globulin present in the blood. Both albumin and globulin are proteins produced by the liver.  


A waste product produced by the liver as it breaks down red blood cells.

Blood Urea Nitrogen (BUN)

A protein waste product removed from the blood by the kidneys. 


An electrically charged mineral (electrolyte) necessary for healthy muscle and nerve function that also helpsmaintain fluid balance.


An electrically charged mineral (electrolyte) vital to a cell’s ability to take in nutrients and remove waste; it is also essential for muscle function and regulating fluid balance.


The primary type of sugar found in your blood.

Total Protein

The total amount of proteins (including albumin) found in the blood that helps determine overall nutritional status.


The main protein that circulates in the blood, which provides tissue nourishment, carries substances (such as hormones and drugs) in the blood, and helps keep fluids within the blood vessels.

Carbon Dioxide (CO2)

A waste product created by the body’s metabolism that helps maintain the body’s acid-base balance (pH) in the form of the electrolyte bicarbonate.

Alanine Aminotransferase (ALT)

An enzyme found mostly in the cells of the liver and kidney.

Aspartate Aminotransferase (AST)

An enzyme found in the cells throughout the body but mostly in the cells of the heart and liver.


A muscle-produced waste product filtered out by the kidneys.

BUN/Creatinine Ratio

A comparison of BUN levels to creatinine levels, two waste products filtered by the kidneys.

Estimated Glomerular Filtration Rate (eGFR)

A calculation (factored from your serum creatinine level, age, and gender) used to determine your level of kidney function; the higher your eGFR number, the better your kidneys are working; low results may be a sign of kidney disease.


Ferritin Test

Iron is an essential mineral that carries oxygen throughout the body in red blood cells. Ferritin is a protein that stores iron for future use when the body needs it most. While an iron test gives the current amount of iron in your blood, this ferritin test measures your body’s overall iron storage and determines if you have a healthy amount of iron in your body. 

When iron levels drop too low, your body cannot make enough hemoglobin to produce the red blood cells it needs. As a result, you may become anemic, which may cause you to feel tired, dizzy, or short of breath. If left untreated, anemia may worsen and lead to additional symptoms. If iron levels get too high, your body absorbs more than is needed, which may be a sign of additional health problems like liver disease, heart problems and diabetes. 

Get a unique view of the iron levels in your body with a ferritin blood test.

A protein that stores iron inside your red blood cells.

About This Test

What's Tested

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Labcorp OnDemand’s Fatigue Test may be right for you if you are experiencing unexplained symptoms of extreme fatigue in association with problems with memory/focus, muscle or joint pain, dizziness, and/or unrefreshing sleep—especially if your symptoms have lasted 6 months or more.²

The fatigue test will give insight into important factors that may be causing your fatigue. Depending on your results, it is recommended you consider your results with a healthcare provider to discuss potential treatment plans.

Your results will provide you with insights regarding your thyroid hormone level, blood cell counts, diabetes risk, electrolyte levels, kidney function, liver enzyme levels and iron storage levels. Any abnormal results could represent an underlying cause for your fatigue and may warrant further evaluation.

Chronic fatigue syndrome (CFS), also known as myalgic encephalomyelitis, can affect all ages, though is more common in people between 40 and 60 years old. Among adults, women are affected more often than men.¹

There is no blood test to diagnose CFS and the cause of the condition is still unknown.² Only a healthcare provider can diagnose CFS by conducting a thorough medical exam and evaluation.² A healthcare provider may consider a diagnosis of chronic fatigue syndrome in patients who experience new onset fatigue that interferes with daily activities, symptoms that persists longer than 6 months, doesn’t improve with rest, worsens with physical exertion, and is associated with poor memory/concentration or dizziness. Because these symptoms overlap with a variety of other health conditions, a healthcare provider must first evaluate for underlying medical conditions that could explain the symptoms.⁴ There is no cure for CFS, however some symptoms can be treated or managed which may provide relief.

If you plan to see your provider with concerns about possible CFS, it may be helpful to write down information about your signs and symptoms, sleep habits, key changes or major stressors in your life, prior to your visit.

Patients should talk with their doctors about all potential therapies because many treatments that are promoted as cures for ME/CFS are unproven, often costly, and could be dangerous.¹

According to the CDC, at this time there is limited data about the long-term effects of COVID-19. Anyone who has been infected with the COVID-19 virus can experience post-COVID conditions. Some people who have been diagnosed with COVID-19 experience long-term symptoms or effects, commonly referred as long COVID or long haul COVID.⁶ These symptoms, which lasts for more than 4 weeks, range from difficulty breathing to brain fog (difficulty thinking or concentrating) to changes in smell and taste. Fatigue or tiredness that interferes with daily life is also a potential long-term effect. While there is no test to diagnose long COVID or post-COVID fatigue, this test can provide information about critical health measures that may be contributing to your fatigue.


If you’re interested in learning more, check out the following resources: 

1) Mayo Clinic. Chronic fatigue syndrome. Mayo Clinic. July 6, 2022.

2) Centers for Disease Control and Prevention (CDC). Symptoms of ME/CFS. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. January 27, 2021.  

3) CDC. Long COVID or Post-COVID Conditions. CDC. September 1, 2022. Accessed December 15, 2022