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Lipoprotein(a): Take charge of your heart health


High Lp(a) affects about 1 in 5 people¹, and often runs in families. It typically has no symptoms and may not show up in standard cholesterol tests, so testing is the only way to know your level. Elevated Lp(a) can raise your risk of heart attack or stroke by up to 4x², but knowing your number puts you in control, so you and your doctor can take steps to lower your overall risk. If you have other factors like high blood pressure, diabetes, or are over 40, testing is even more important. Get started today with the same trusted test used by doctors.

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What is Lp(a)? Understanding Lipoprotein(a) and why it’s an important screening test

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Elevated Lp(a) levels and the importance of a heart-healthy lifestyle

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Frequently Asked Questions

  • Cholesterol is a waxy, fatty substance made by your liver. Your body needs it to build cells and make vitamins and other hormones. There is “good” and “bad” cholesterol in the body but too much cholesterol can pose a problem.

     

    Lipoproteins include LDL, HDL, Lp(a). Lp(a) is a specific LDL that carries “bad” cholesterol to the cells in your arteries. A routine cholesterol test, also called a lipid profile or lipid panel, measures your LDL, HDL, total cholesterol, and triglycerides levels.³ However, the test doesn’t measure the number of each lipoprotein that can lead to heart disease, including Lp(a). Even if your LDL levels are in the normal range, Lp(a) levels may still be high. This means your risk for heart disease and stroke could still be high.

  • Current guidelines from the American Heart Association recommend every adult have their Lp(a) levels tested at least once in their lifetime as part of a cardiovascular risk assessment.³


    In addition to general screening, this test may be especially important for individuals with higher cardiovascular risk, including those who have:

    • Family or personal history of premature heart disease (under 55 for men and under 65 for women)
    • Family history of high Lp(a)
    • High LDL cholesterol, even if you take medicine to lower it
    • Heart or blood vessel disease (especially if your cholesterol and triglyceride levels are normal without taking medicine to lower them)
    • Familial hypercholesterolemia (inherited high cholesterol)
    • A personal history of multiple heart attacks and/or procedures to treat blocked arteries


    Lp(a) levels are largely determined by genetics and typically remain stable throughout life, so a one-time test is often sufficient to identify long-term cardiovascular risk.

  • Lp(a) levels greater than or equal to 75.0 nmol/L may indicate a risk factor for heart disease. Your risk of heart disease and stroke may be higher if Lp(a) levels greater than or equal to 125 nmol/L.³ Lp(a) levels in different ethnic populations can vary widely. Speak with your healthcare provider about various risk factors you may have.

  • Your results will tell you the level of lipoprotein(a) in your blood sample. A high Lp(a) level indicates you may have an increased risk of heart attack, heart disease, stroke, and other diseases of the blood vessels. There are currently no targeted treatments to lower Lp(a) levels at this time. However, you should share any abnormal results with your healthcare provider to discuss other treatments (such as statins) or ways to reduce your overall risk of heart disease including lifestyle changes (such as well-balanced nutrition and physical activity).

  • Your testing will be performed in a CLIA-certified clinical laboratory. Labcorp provides leading-edge medical laboratory tests and services through a national network of primary clinical laboratories and specialty testing laboratories. Our labs perform regular quality assurance testing to ensure our results are accurate.

  • Your results will be provided to you through our secure online portal to view or print. Results are also made available through a secure portal to the independent healthcare provider who placed your test order.  If you are accessing your results through your Labcorp Patient™ account, all users linked to the account will have access to all OnDemand test results. Results may also be provided to a local, state, and/or federal health authority; for example, many states require the testing laboratory and physician to report test results for certain communicable diseases, such as COVID-19, to local or state health departments.
     

    If you have questions or comments regarding the Labcorp Notice of Privacy Practices, or have a complaint about our use or disclosure of your PHI or our privacy practices, please contact: privacyofficer@labcorp.com, call us at (877) 234-4722 (877-23-HIPAA) and ask for the Labcorp HIPAA Privacy Officer, or send a written request to: HIPAA Privacy Officer, Labcorp, 531 South Spring Street, Burlington, NC 27215. You also may file a complaint with the Secretary of the U.S. Department of Health and Human Services.

  • Visit the Labcorp OnDemand® website to browse and purchase laboratory tests and create your Labcorp Patient™ account to view your results. All Labcorp OnDemand testing requires an order from an authorized healthcare professional. For your convenience, Labcorp OnDemand has contracted with independent professional entities (collectively, Providers) to deliver healthcare provider services. Visit a Labcorp location for sample collection; or, if using an at-home collection kit, collect your sample yourself. We’ll let you know when your results are ready and can be accessed through your MyLabcorp™ account.

References:
 

1. Family Heart Foundation. Diagnosing High Lipoprotein (a). https://familyheart.org/diagnosing-high-lipoproteina

2. Centers of Disease Control. About Lipoprotein (a). https://www.cdc.gov/heart-disease-family-history/about/about-lipoprotein-a.html

3. American Heart Association. Lipoprotein (a). https://www.heart.org/en/health-topics/cholesterol/genetic-conditions/lipoprotein-a