This panel includes testing related to:
- Heart health (lipids, ApoB, and more)
- Kidney health (ACR, and eGFR)
- Liver health (enzymes, proteins, and more)
Measure heart, kidney, and liver health markers in one convenient panel.
Customize Your Test
The Vital Organ Function Test is a comprehensive panel that measures key biomarkers related to heart, liver, and kidney health. It combines several common lab tests such as lipids, apolipoprotein B (ApoB), inflammation, albumin-to-creatinine ratio (ACR), liver enzymes, and proteins to help assess the health and function of vital organs, giving you insights into overall health and potential risks associated with these organs. Results may help you better understand these organ functions and can be used as part of a broader view of your health.
This panel includes evaluation of:
Note: This test is not intended to diagnose CVD, type 2 diabetes, liver disease, or other conditions.
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Preparation: Fast for 12-14 hours (no food or drink, except water) before sample collection.
Your heart, kidneys, and liver work closely together to support circulation, metabolism, and detoxification. Testing markers from these systems together may provide a more complete view of your health.
By understanding your levels for key indicators related to heart health, liver and kidney function, you can take proactive steps to manage your health. This organ health test can help you and your healthcare provider detect early signs of potential health problems, empowering you to address these risks with lifestyle changes and preventive treatments.
Assessing your organ health is an important step in taking care of your body. Habits such as exercise and well-balanced nutrition can help maintain vital organ health. You can share your results with a healthcare provider who can interpret them in the context of your overall health, risk factors, and any symptoms.
1. Centers for Disease Control and Prevention. Chronic Kidney Disease in the United States, 2021. Centers for Disease Control and Prevention website. Reviewed July 12, 2022. Accessed November 14, 2022. https://www.cdc.gov/kidney-disease/php/data-research
2. The National Kidney Foundation. Estimated Glomerular Filtration Rate (eGFR). Accessed September 8, 2023. https://www.kidney.org/atoz/content/gfr
3. The National Kidney Foundation. 10 Signs You May Have Kidney Disease. December 17, 2020. Accessed September 8, 2023. https://www.kidney.org/news/ekidney/august14/10_Signs_You_May_Have_Kidney_Disease
4. National Kidney foundation. Know Your Kidney Numbers: Two Simple Tests. National Kidney Foundation. Published October 17, 2018. https://www.kidney.org/atoz/content/know-your-kidney-numbers-two-simple-tests
5. National Institutes of Health (NIH). Definition & Facts of NAFLD & NASH. Last reviewed April 2021. Accessed May 15, 2023. https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash/definition-facts.
6. American Heart Association. About Metabolic Syndrome. www.heart.org. 2016. Accessed May 15, 2023. https://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome.
7. Rinella ME, Lazarus JV, Ratziu V, et al. A multi-society Delphi consensus statement on new fatty liver disease nomenclature. Hepatology. 2023.
8. Cusi K, Isaacs S, Barb D, et al. American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD). Endocr Pract. 2022;28(5):528-562. doi:10.1016/j.eprac.2022.03.010
9. ElSayed NA, Aleppo G, Aroda VR, et al. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes—2023. Diabetes Care. 2022;46(Supplement_1):S49-S67. doi: https://doi.org/10.2337/dc23-s004
10. Nassir F, Rector RS, Hammoud GM, Ibdah JA. Pathogenesis and Prevention of Hepatic Steatosis. Gastroenterol Hepatol. 2015;11(3):167-175.
<p>1. Centers for Disease Control and Prevention. Chronic Kidney Disease in the United States, 2021. Centers for Disease Control and Prevention website. Reviewed July 12, 2022. Accessed November 14, 2022. <a rel="noopener noreferrer" title="data-research" target="_blank" href="https://www.cdc.gov/kidney-disease/php/data-research">https://www.cdc.gov/kidney-disease/php/data-research</a></p> <p>2. The National Kidney Foundation. Estimated Glomerular Filtration Rate (eGFR). Accessed September 8, 2023. <a rel="noopener noreferrer" title="kidney.org" target="_blank" href="https://www.kidney.org/atoz/content/gfr">https://www.kidney.org/atoz/content/gfr</a></p> <p>3. The National Kidney Foundation. 10 Signs You May Have Kidney Disease. December 17, 2020. Accessed September 8, 2023. <a rel="noopener noreferrer" title="Kidney_Disease" target="_blank" href="https://www.kidney.org/news/ekidney/august14/10_Signs_You_May_Have_Kidney_Disease">https://www.kidney.org/news/ekidney/august14/10_Signs_You_May_Have_Kidney_Disease</a></p> <p>4. National Kidney foundation. Know Your Kidney Numbers: Two Simple Tests. National Kidney Foundation. Published October 17, 2018. <a rel="noopener noreferrer" title="two-simple-tests" target="_blank" href="https://www.kidney.org/atoz/content/know-your-kidney-numbers-two-simple-tests">https://www.kidney.org/atoz/content/know-your-kidney-numbers-two-simple-tests</a></p> <p>5. National Institutes of Health (NIH). Definition & Facts of NAFLD & NASH. Last reviewed April 2021. Accessed May 15, 2023. <a rel="noopener noreferrer" title="definition-facts" target="_blank" href="https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash/definition-facts">https://www.niddk.nih.gov/health-information/liver-disease/nafld-nash/definition-facts</a>.</p> <p>6. American Heart Association. About Metabolic Syndrome. <a rel="noopener noreferrer" title="heart.org" target="_blank" href="https://www.heart.org/">www.heart.org</a>. 2016. Accessed May 15, 2023. <a rel="noopener noreferrer" title="metabolic-syndrome" target="_blank" href="https://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome">https://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome</a>.</p> <p>7. Rinella ME, Lazarus JV, Ratziu V, et al. A multi-society Delphi consensus statement on new fatty liver disease nomenclature. <i>Hepatology</i>. 2023.</p> <p>8. Cusi K, Isaacs S, Barb D, et al. American Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD). <i>Endocr Pract</i>. 2022;28(5):528-562. doi:10.1016/j.eprac.2022.03.010</p> <p>9. ElSayed NA, Aleppo G, Aroda VR, et al. Comprehensive Medical Evaluation and Assessment of Comorbidities: Standards of Care in Diabetes—2023. Diabetes Care. 2022;46(Supplement_1):S49-S67. doi: <a href="https://doi.org/10.2337/dc23-s004"><b>https://doi.org/10.2337/dc23-s004</b></a></p> <p>10. Nassir F, Rector RS, Hammoud GM, Ibdah JA. Pathogenesis and Prevention of Hepatic Steatosis. <i>Gastroenterol Hepatol</i>. 2015;11(3):167-175.</p>
Simply purchase this test online. A healthcare provider will review and approve your test requests; no healthcare provider visit is required.
Visit a Labcorp location near you for sample collection. Visits may be scheduled online.
View your easy-to-read results online in your Labcorp Patient™ account, including Linked Accounts. For certain results that require prompt attention, you will also be contacted by phone or mail.
Each result is reported with a reference range to indicate whether levels fall within expected values. Results should be reviewed together and interpreted by a healthcare provider, who can explain what they may mean based on your symptoms, health history, and other lab tests.
This panel includes testing related to:
Adults interested in learning more about biomarkers related to heart, kidney, and liver health or those following up on previous lab results may consider this panel as part of a proactive approach to health.
Some liver and kidney conditions may not cause noticeable symptoms, especially in early stages. As these conditions progress, some people may experience changes that reflect how these organs are functioning.
Possible kidney-related symptoms may include fatigue, difficulty concentrating, swelling in the legs or ankles, changes in urination (such as frequency or appearance), or muscle cramps. In some cases, early kidney disease has no symptoms, and lab testing can help screen for kidney disease.1,3
Possible liver-related symptoms can include feeling tired, abdominal discomfort, dark-colored urine, or yellowing of the skin or eyes (jaundice). Conditions such as fatty liver disease are often linked to metabolic factors like obesity, diabetes, or high cholesterol and may develop without clear symptoms.4,5
Possible heart-related symptoms may include chest discomfort, shortness of breath, fatigue, dizziness, or swelling in the legs. However, some heart conditions can also develop gradually without obvious symptoms early on.
Because these symptoms can be subtle or overlap with other conditions, it’s important to discuss any concerns with your healthcare provider. Lab testing may provide additional information into how your liver and kidneys are functioning as part of a broader health evaluation.
Your testing will be performed in a CLIA-certified clinical laboratory. Labcorp provides leading-edge medical laboratory tests and services through a national network of primary clinical laboratories and specialty testing laboratories. Our labs perform regular quality assurance testing to ensure our results are accurate.
Your results will be provided to you through our secure online portal to view or print. Results are also made available through a secure portal to the independent healthcare provider who placed your test order. If you are accessing your results through your Labcorp Patient™ account, all users linked to the account will have access to all OnDemand test results. Results may also be provided to a local, state, and/or federal health authority; for example, many states require the testing laboratory and physician to report test results for certain communicable diseases, such as COVID-19, to local or state health departments.
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Visit the Labcorp OnDemand® website to browse and purchase laboratory tests and create your Labcorp Patient™ account to view your results. All Labcorp OnDemand testing requires an order from an authorized healthcare professional. For your convenience, Labcorp OnDemand has contracted with independent professional entities (collectively, Providers) to deliver healthcare provider services. Visit a Labcorp location for sample collection; or, if using an at-home collection kit, collect your sample yourself. We’ll let you know when your results are ready and can be accessed through your Labcorp Patient™ account.
To align with clinical best practices, we’ve set an age maximum of 100 for consumer-initiated testing. This limit was set to encourage individuals in more advanced age groups - who may have complex medical needs - to receive personalized guidance about testing from their healthcare providers.